Health authorities in Canada said the second reported fatal adverse reaction occurred on January 30 after a donation at Grifols’ Innovation Drive location in Winnipeg.
The agency did not release details about the identity of the second person.
The federal regulator said it has not established a link between the plasma donations and the deaths and is still assessing the reports.
It added that it sent staff to inspect the clinics following the incidents.
Plasma donation is similar to blood donation, but after blood is drawn, the plasma, a pale yellow liquid rich in antibodies, is separated while the red blood cells are returned to the donor’s body.
The process is generally considered safe.
Plasma contains immunoglobulins that help strengthen the immune system and clotting factors that help control bleeding. These components are used to treat infections, bleeding disorders and liver disease.
However, donors are warned that side effects can occur, including fatigue, dehydration, dizziness, bruising and fainting.
Grifols, which has operated in Winnipeg since 2022 after acquiring Canadian Plasma Resources, expressed condolences to the families of the deceased.
In a statement, the company said based on available information, “we have no reason to believe that there is a correlation between the donors’ passing and plasma donation”.
The company said all donors undergo a detailed health history review and physical examination before being cleared to donate.
Plasma donors at the centres can receive honorarium payments of up to $100 per donation, with additional bonuses offered for frequent donations.
Under Canadian regulations, all plasma collection facilities must report any serious reaction experienced by a donor during the procedure or within 72 hours after donation to Health Canada.
